LETTER TO THE SHAREHOLDERS

22 September, 2025

Napoleonville, LA IFUS:OTCID

In the pursuit of plausible science that explains reports of successful application of the IFUS Product Lines to humans, animals, and plants, the IFUS Scientific Team continues its pursuit for the truth. The individual nature of any aspect of science can be complex and daunting within itself. The individual nature of that respective science, when placed into the context of interrelated science, becomes a Herculean feat…yet one that IFUS remains committed so as to create sales support, resulting in the successful application of our product lines. 

For years now, cattle being fed SGP+™ are consistently reported to lack flies both on their hides as well on the Score 3 Manure Pats (See Picture 1 and 2, respectively) 

Picture 1:  

Picture 2:  

Additionally, no fly larvae are found within the Score 3 Manure Pats. (See Picture 3 below of stirred Score 3 Manure Pat) 

The science is suggesting that this is due to IFUS’s Proprietary Formulation and Product Processing Technologies. SGP+™ is believed to provide to the cattle a ration mix, whereby the lignin is both degraded and depolymerized, combined with phytochemicals found in Sugarcane Bagasse, Chios Mastic Gum, and Carob…all of which are reported to repel flies as well as certain insects and bugs.  

Furthermore, when compared to starting ration mix, Cumberland Valley Analytical Services has provided data indicating that the lignin in the Score 3 Manure Pats has been reduced from approximately 20% to as low as 6%. What lignin remains seems to be derived from undigested corn hulls visible within the Score 3 Manure Pats. 

Flies and other insects and bugs require lignin for the larvae to survive and thrive. The lack of larvae in the Score 3 Manure Pats indicates that lignin levels are inadequate for larval development. Hence, mature flies cannot successfully be produced from larvae as the larvae do not have enough nutrition to support that development. Additionally, the phytochemicals known to exist in the Mastic, Carob, and De-polymerized Sugarcane Bagasse have been shown to possess antilarcividal properties as well as repellency to flies, insects, and bugs. The IFUS Scientific Team continues to work towards a greater understanding of these individual and possibly collective interactions. 

In this vein, reports from customers of the lack of select insect and bug presence as well as plant damage on certain plants, trees, and shrubs are of no surprise. These reports further substantiate the thinking of the IFUS Scientific Team and its offering of plausible scientific evidence as to the efficacy of SGP+™, 

SupremeAG™, and Nutri-Mastic™ in reducing and/or eliminating unwanted pest is an “All-Natural, Eco-Friendly, Cost-Effective, and Functional Manner.” (See 

Picture 4 of Peaches Grown at IFUS Test Farm about 18.25 miles SSW of NOLA) 

Applying SupremeAG™ to iron-loving, acid-loving plants high in flavonoids appears to be creating: 

Furthermore, the application of a few drops of Nutri-Mastic™ on cut flowers is creating longer lasting blooms in the vase for greater enjoyment and an improved return on this kind of investment. (See Picture 6 & 7 of Cut Flowers given for 

Mother’s Day and then lasting for weeks not days after being treated with NutriMastic) 

Picture 6: Mother’s Day Flowers 11May25 

Picture 7: 29May2025 

These results are indicative of the interplay and interconnection of beneficial phytochemicals enriched in the soil through the application of SupremeAG™ as soil amendment and/or mulch, as well as the subsequent release of the phytochemicals and/or their metabolized alternatives in the creation of healthier, insect and disease-resistant plants…all delivered by an eco-friendly and costeffective product.  

As one example among an emerging plethora, the science is suggesting to IFUS that the phytochemicals in Chios Mastic Gum mirrors the same or similar phytochemicals in Carob, and Sugarcane Bagasse (untreated and lignin-degraded and depolymerized). The content below can be found in the IFUS White Paper Part 1a Screwworm Fly (Rev.5-5Jun25-ifus) at: https://www.impactfusionbrands.com/knowledge-base/?top-category=studies

IFUS Point 4b-2: Does Pistacia lentiscus (Chios Mastic Gum Trees) have insecticidal properties?  

IFUS Point 4b-2.1: “Yes, Pistacia lentiscus has insecticidal properties.

Research has shown that the fruit extract of Pistacia lentiscus is toxic to the larvae of the grapevine moth, Lobesia botrana, indicating its potential as an insecticide. Additionally, the essential oil from this plant has been found to exhibit acaricidal effects against red poultry mites, Dermanyssus gallinae, suggesting its effectiveness in controlling certain insect pests (1,2) 

IFUS Point 4b-2.1a: Ref. (1) Insecticidal Effect of Pistacia lentiscus (Anacardiaceae) Metabolites against Lobesia botrana (Lepidoptera: Tortricidae), Ioanna Dasenak, et.al, Agronomy 2022, 12(4), 755; https://doi.org/10.3390/agronomy12040755

IFUS Point 4b-2,1b: Ref. (2) Pistacia lentiscus essential oil and its pure active components as acaricides to control Dermanyssus gallinae (Acari: Mesostigmata), Dhouha Alimi, et.al., Veterinary Parasitology, 

Volume 322, October 2023, 110028, 

https://doi.org/10.1016/j.vetpar.2023.110028

IFUS Point 4b-2.2: What chemical in Pistacia lentiscus (i.e., Mastic Gum) repels insects?

IFUS Point 4b-2.2a: Β-caryophyllene: “The chemical in Pistacia lentiscus that repels insects is β-caryophyllene, which is the most effective component of its essential oil. This essential oil has shown high repellent activity against various insect pests, making it a potential eco-friendly alternative to chemical repellents.” (Pistacia lentiscus essential oil has repellent effect against three major insect pests of pasta, Hind 

Houria Bougherra, et.al., Industrial Crops and Products, 

Volume 63, January 2015, Pages 249-255) 

IFUS Point 4b-2.2b: What do we know about β-caryophyllene? “Caryophyllene, more formally (−)-β-caryophyllene (BCP), is a natural bicyclic sesquiterpene that occurs widely in nature. Caryophyllene is notable for having a 10yclobutene ring, as well as a trans-double bond in a 9-membered ring, both rarities in nature.”  

(Sell, Charles S. (2006). “Terpenoids”. Kirk-Othmer Encyclopedia of Chemical Technology. 

Doi:10.1002/0471238961.2005181602120504.a01.pub2. ISBN 0471238961.) 

IFUS Point 4b-2.2c: “It is a constituent of many essential oils, especially clove oil, the oil from the stems and flowers of Syzygium aromaticum (cloves), the essential oil of Cannabis sativa, copaiba, rosemary, and hops. Sell, Charles S. (2006). 

‘Terpenoids’.”(Kirk-Othmer Encyclopedia of 

ChemicalTechnology.doi:10.1002/0471238961.2005181602120 504.a01.pub2. ISBN 0471238961. 

IFUS Point 4b-2.2d: “Caryophyllene is one of the chemical compounds that contributes to the aroma of black pepper. 

Jirovetz, L., et.al, (November 2002). “Aroma compound analysis of Piper nigrum and Piper guineense essential oils from Cameroon using solid-phase microextraction– gas chromatography, solid-phase microextraction–gas chromatography–mass spectrometry and olfactometry”.

Journal of Chromatography A. 976 (1–2): 265–275. 

Doi:10.1016/S0021-9673(02)00376-X. PMID 12462618. 

IFUS Point 4b-3.1: Furthermore, there are suggested links to Gallic Acid and Arachidonic acid (AA), a precursor for eicosanoids. Eicosanoids are said to be critical to fly immunity. Hence, this is another possible pathway that warrants further investigation. With that said, it is established that, “Gallic acid can impair the growth of insect larvae without causing significant harm to their parasitoid wasps (1).” This is but one more of a series of studies suggesting Gallic Acid’s anti-larval efficacy (and explored in the sections dedicated to Gallic Acid). 

IFUS Point 4b-3.1a: Ref. (1) Effect of gallic acid on the larvae of Spodoptera litura and its parasitoid Bracon hebetor, Abhay Punia, et.al., Sci Rep. 2021 Jan 12;11:531. doi: 

10.1038/s41598-020-80232-1, PMCID: PMC7803745  PMID: 

33436810 

IFUS Point 4g-3: Furthermore, “Gallic acid can impair the growth of insect larvae without causing significant harm to their parasitoid wasps.” (“Effect of gallic acid on the larvae of Spodoptera litura and its parasitoid Bracon hebetor,” Abhay Punia, et.al., Sci Rep. 2021 Jan 12;11:531. doi: 

10.1038/s41598-020-80232-1, PMCID: PMC7803745  

PMID: 33436810 

IFUS Point 4g-3a: The larvicidal nature of Gallic Acid found in Carob and Mastic and produced depolymerized lignin from Sugarcane Bagasse will be explored in a later topic as it represents another layer of fascinating biochemistry. However, it is worthy to comment that these continued synergies provided by nature to produce and eco-friendly and cost-effective solution to both the greater fly problem as well as the New World Screwworm Fly through enhanced Bovine Herd Performance seems to be at the very least worthy of serious consideration and deeper scientific exploration. Of course, there’s nothing like results to prove a point…that is, a lack of flies on the herds and the manure, as well as lack of fly larvae in the manure. 

IFUS Point 7f: “Β-caryophyllene affects gustatory receptors (GRs) in flies. β-caryophyllene affects gustatory receptors (GRs) in flies (1,2,5). GRs are members of a large G-protein coupled receptor family and are phylogenetically different from taste receptors in most other animals2. βcaryophyllene is a natural bicyclic sesquiterpene found in cannabis and non-cannabis plants (3.4).” 

IFUs Point 7f-1: Ref (1) Recent Advancements in Studies on 

Chemosensory Mechanisms Underlying Detection of 

Semiochemicals in Dacini Fruit Flies of Economic Importance (Diptera: Tephritidae), Hajime Ono, et.al., Insects. 2021 Jan 26;12(2):106. doi: 10.3390/insects12020106, PMCID: 

PMC7911962  PMID: 33530622 

IFUS Point 7f-2: Ref (2) Molecular and Cellular Designs of Insect Taste Receptor System, Front Cell Neurosci. 2010 Jun 18;4:20. doi: 10.3389/fncel.2010.00020, PMCID: PMC2896210  PMID: 20617187

IFUS Point 7f-3: Ref (5) Multiple gustatory receptors required for the caffeine response in Drosophila, Youngseok Lee, et.al., Proc Natl Acad Sci U S A. 2009 Feb 25;106(11):4495–4500. doi: 

10.1073/pnas.0811744106, PMCID: PMC2657413  PMID: 

19246397 

IFUS Point 7f-4: Ref (3) A focused review on CB2 receptorselective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid, Hebaallah Mamdouh Hashiesh, et.al., Biomed Pharmacother. 2021 Aug:140:111639. doi: 10.1016/j.biopha.2021.111639. PMID: 34091179 DOI: 

10.1016/j.biopha.2021.111639 

IFUS Point 7f-5: Ref (4) β-Caryophyllene: A Sesquiterpene with 

Countless Biological Properties, Fabrizio Francomano, et.al., 

Applied Sciences, December 20199(24), DOI:10.3390/app9245420 

Hence, the science continues to offer to the IFUS Scientific Team plausible explanations as to the success of SupremeAG™, as well as other members of the IFUS Product Line. The interrelationship of the phytochemicals seems to impact in a positive manner humans, animals, and plants…or so suggests the science. 

”It is most rewarding to learn of success stories from our customers. Knowing that your company is making a difference in the lives of those customers has me evercommitted. Your Scientific Team remains highly engaged and broadening its 

outreach to other professionals to gain their guidance. Your Product Line is expanding and now includes Equine Intact™, SGP+E™, Supreme(AG)™, SGP+™, and Nutri-Mastic™. We are excited about these products and remain eager to learn of the successful application of each.” 

Once more, we are back to work so that your company’s mission of Research, Validation, and Commercialization of Technologies fulfills your company’s vision of products that improve the health and well-being of humans, animals, and plants…products that actually create a profitable reality for you.

Back to work! 

For our customers of both Intact Digest™ and Intact Endurance™ you may now send your testimonials to: 

mwalther@impactfusionintl.com   We can also be reached at 1-800-775-4130 seven days a week. 

About Impact Fusion Internaonal Inc. 

Impact Fusion Internaonal, Inc. is in the business of markeng products in the “Health and Wellness” sector of all internaonal markets. It is the company’s mission to invent, develop and market these proprietary products worldwide for the health and well-being of humans and animals. 

The informaon contained in this release includes some statement that are not purely historical and that are “forward-looking statements.” Such forward-looking statements include, but are not limited to, statements regarding our and their management’s expectaons, hopes, beliefs, intenons or strategies regarding the future, including our financial condion, results of operaons. In addion, any statements that refer to projecons, forecasts or other characterizaons of future events or circumstances, including any underlying assumpons, are forward-looking statements. The words “ancipates,” “believes,” 

“connue,” “could,” “esmates,” “expects,” “intends,” “may,” “might,” “plans,” “possible,” “potenal,” “predicts,” “projects,” “seeks,” “should,” “would” and similar expressions, or the negaves of such terms, may idenfy forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. The forward-looking statements contained in this release are based on current expectaons and beliefs concerning future developments and the potenal effects on the pares and the corporate and administrave transacons. Forward-looking statements involve known and unknown risks, uncertaines and other factors, which may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements and represent our management’s beliefs and assumpons only as of the date hereof. Except as required by law, we assume no obligaon to update these forward-looking statements, even if new informaon becomes available in the future. 

Contact:

Impact Fusion Internaonal Inc. 

204 Highway 1011 

Napoleonville LA 70390 

1-800-775-4130

Email: mwalther@impacusionintl.comhtps://www.impacusionbrands.com/brands 

Updates can be found at the official Impact Fusion Twiter account @impacusionI 

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