Napoleonville, LA IFUS:OTCID

At the beginning of this year, a commitment was made to you our shareholders that your company would create a dedicated effort to expand “Market Presence” and sales of the IFUS Product Lines. Where much work remains to be done, we are pleased to announce that Intact Digest™ can now be found on Amazon.

https://a.co/d/5HVwd3B

Per your IFUS Website: “Intact Digest™ with Nutri-Mastic™ is perfectly balanced with Ionic Minerals & Mastic Gum. This Proprietary Blend combination helps improve delivery of Nutritional Absorption, Anti-Oxidants, Anti-Inflammatory Properties & Natural Anti-Bacterial benefits into the cellular system, supporting Digestive function and Optimal Health. Intact Digest™ helps provide relief from occasional constipation, cramping, fatigue and heartburn. It supports dairy digestion, hair, skin and nail growth and is safe for daily use. It is not a laxative or harsh fiber.”

To date, we know of NO other product on the market that combines Chios Mastic Gum with naturally sourced Ionic Minerals into a formulation that can be applied orally and topically.

Additionally, where much science is required to substantiate claims of health improvements and over-all well-being by customers applying Intact Digest with Nutri-Mastic™ as part of their nutritional supplementation and/or as a topical treatment, customers are in fact sending in testimonials and pictures to that end.

Our IFUS Scientific Team contends that many of the health issues facing humans today begins with poor gut health.

Mohammad Shabani, et.al. published an article: “The relationship between gut microbiome and human diseases: mechanisms, predisposing factors and potential intervention,” Front Cell Infect Microbiol. 2025 May 6;15:1516010. doi:

10.3389/fcimb.2025.1516010.

The Shabani Team writes in their abstract:

The complex interrelation of gut microbiota with human health underlines the profound influence this microbial ecosystem has on mechanisms of disease and wellness. The gut microbiome profoundly impacts various human diseases, encompassing gastrointestinal disorders, metabolic disorders, neurological disorders, and immune-related diseases. Gastrointestinal disorders are closely linked to microbial imbalances in the gut. Metabolic disorders, including obesity and type 2 diabetes, are influenced by the gut microbiota’s role in energy regulation and glucose metabolism. Furthermore, the gut-brain axis highlights the correlation between gut microbiota and neurological conditions such as Alzheimer’s and Parkinson’s. Moreover, the gut microbiome assumes a pivotal function in regulating the immune system, whereby dysbiosis is implicated in developing immunological-related ailments, including allergies and autoimmune disorders. Predisposing factors, including diet, medicines, lifestyle, and environmental influences, are described as having an important role in the composition of the gut microbiome. By understanding these factors, we can get valuable insights into how to intervene to reduce the chances of a disease. Current interventions, including probiotics, prebiotics, fecal microbiota transplants, and lifestyle modification, show promise, but there are still challenges and unanswered questions in this evolving field that may lead to improvements. This review interrelates the complicated gut microbiome with various human diseases, mechanisms, predisposing factors, and potential interventions.” See Fig.1 below:

Figure 1.

Gut microbiome-associated diseases. Front Cell Infect Microbiol. 2025 May 6;15:1516010. doi:

10.3389/fcimb.2025.1516010

Our IFUS Scientific Team believes that this is associated with gut mitochondria. A paper published by Bo Zhou and Rong Tian (“Mitochondrial dysfunction in pathophysiology of heart failure,”) August 2018, The Journal of Clinical Investigation, 128(9) (DOI:10.1172/JCI120849) provides an illustration in support of the IFUS’ Scientific Team’s contention:

“An overview of mitochondrial function in health and disease. Mitochondria are known as the powerhouse of the cell. Under normal conditions, oxidative metabolism in mitochondria produces ATP; it also produces heat in certain specialized cell types, such as brown adipocytes. In addition to generating ATP, intermediate metabolism in the mitochondria produces metabolites for biosynthesis, protein modification, and signal transduction. Oxidative phosphorylation is coupled with generation of reactive oxygen species (ROS), which can either serve as molecular signals or cause cell damage and cell death. Mitochondrial metabolism is stimulated by calcium, but under pathological conditions, calcium overload can trigger the opening of the mitochondrial permeability transition pore (mPTP). The release of mitochondrial content, such as cytochrome c, induces apoptosis, or the loss of membrane potential (a consequence of prolonged mPTP opening) causes ATP deprivation and necrosis. Leak of damage-associated molecular patterns (DAMPs), such as mitochondrial DNA and peptides, or excessive ROS generation also causes inflammation that results in further tissue damage. The transition of mitochondria from a powerhouse to a death engine is key to the pathogenesis of many diseases, including heart failure (also see Figure 3).”

“This expanded market presence resulting in expanded sales of Intact Digest™ is indeed exciting. Furthermore, our internal and external IFUS Scientific Teams are compiling reports from customers so as to review and offer plausible scientific evidence, like that shown above, in support of the efficacy of Intact Digest™. Yet, what is most rewarding is the possibility of relief to our fellow humans who suffer daily from ailments…and do so without hope. We believe we can find a way to provide relief to these individuals, while doing so in a cost-effective, eco-friendly manner in ways that actually work. With new information and reported successes, we will strive to uncover scientific truths, many of which are being overlayed to the overall IFUS Product Line. As before, with each bit of information, we become better informed as to how we might apply our products as the break-through technologies we believe each to be. Our ability to use this information to generate sales that will create profitable outcomes for your company is encouraging. We still have much work to do, but are relentless in getting the job done for you and

for all of our stakeholders,” said Marc Walther, CEO of Impact Fusion International.

Once more, we are “Back to work!”

The information provided is for informational purposes only and is not intended as medical advice. Our products are not intended to diagnose, treat, cure, or prevent any medical condition. Always consult with a qualified healthcare professional before starting any new supplement, diet, or health regimen.

For our customers of both Intact Digest™ and Intact Endurance™ you may now send your testimonials to:

mwalther@impactfusionintl.com We can also be reached at 1-800-775-4130 seven days a week.

About Impact Fusion International Inc.

Impact Fusion International, Inc. is in the business of marketing products in the “Health and Wellness” sector of all international markets. It is the company’s mission to invent, develop and market these proprietary products worldwide for the health and well-being of humans and animals.

The information contained in this release includes some statement that are not purely historical and that are “forward-looking statements.” Such forward-looking statements include, but are not limited to, statements regarding our and their management’s expectations, hopes, beliefs, intenons or strategies regarding the future, including our financial condition, results of operations. In addion, any statements that refer to projections, forecasts or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. The words “ancipates,” “believes,”

“continue,” “could,” “estimates,” “expects,” “intends,” “may,” “might,” “plans,” “possible,” “potential,” “predicts,” “projects,” “seeks,” “should,” “would” and similar expressions, or the negatives of such terms, may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. The forward-looking statements contained in this release are based on current expectations and beliefs concerning future developments and the potential effects on the pares and the corporate and administrative transacons. Forward-looking statements involve known and unknown risks, uncertainties and other factors, which may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements and represent our management’s beliefs and assumpons only as of the date hereof. Except as required by law, we assume no obligation to update these forward-looking statements, even if new information becomes available in the future.

Contact:

Impact Fusion Internaonal Inc.

204 Highway 1011

Napoleonville LA 70390

1-800-775-4130

Email: mwalther@impacusionintl.comhtps://www.impacusionbrands.com/brands

Updates can be found at the official Impact Fusion Twiter account @impacusionI

#Foodintelligence #NewMexico #healthiercatle #Screwworms

#Intact #Digeson #Endurance #Germany #Colorado

#legislaon #bagasse #drought #SUAREC #Louisiana

#greenhousegases #methanegas #catle #dairy #Texasfloods

#Texaswildfires $Waygu #India #Black Farmers Naonal

Associaon #Supreme AG™ #SGP+™ #Oklahoma

#KECO 96.5 FM radio #India #Australia #Brazil #Argenna #Canada #Vietnam